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arachidonate biosynthesis

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
a_1-oleoyl-2-acyl-[glycerolipid] + reduced_ferredoxin_[iron-sulfur]_cluster + O2 + H+ <=> a_1-linoleoyl-2-acyl-[glycerolipid] + oxidized_ferredoxin + H2O 1.14.19.45 sn-1 oleoyl-lipid 12-desaturase
1.14.19.6 acyl-CoA (9+3)-desaturase


palmitoyl-[acyl-carrier_protein] + malonyl-CoA <=> 3-oxooctadecanoyl-[acyl-carrier_protein] + CO2 + CoA 2.3.1.41 beta-ketoacyl-[acyl-carrier-protein] synthase I

palmitoyl-[acyl-carrier_protein] + H2O <=> fatty_acid + [acyl-carrier_protein] + H+ 2.3.1.85 fatty-acid synthase system
3.1.2.14 oleoyl-[acyl-carrier-protein] hydrolase
3.1.2.21 dodecanoyl-[acyl-carrier-protein] hydrolase



oleic_acid + CoA + ATP <=> oleoyl-CoA + AMP + diphosphate 1.13.12.7 firefly luciferase
6.2.1.12 4-coumarate---CoA ligase
6.2.1.3 long-chain-fatty-acid---CoA ligase
6.2.1.B3




ATP + 8,11,14-eicosatrienoic_acid + CoA <=> AMP + diphosphate + 8,11,14-eicosatrienoic_acid 6.2.1.3 long-chain-fatty-acid---CoA ligase

a_very-long-chain_trans-2,3-dehydroacyl-CoA + NADPH + H <=> behenoyl-CoA + NADP+ 1.3.1.93 very-long-chain enoyl-CoA reductase

a_1-linoleoyl-2-acyl-[glycerolipid] + O2 + reduced_ferredoxin_[iron-sulfur]_cluster + H+ <=> a_gamma-linolenoyl-[glycerolipid] + H2O + oxidized_ferredoxin 1.14.19.46 sn-1 linoleoyl-lipid 6-desaturase

oleoyl-[acyl-carrier_protein] + H2O <=> [acyl-carrier_protein] + oleic_acid + H+ 3.1.2.14 oleoyl-[acyl-carrier-protein] hydrolase
3.1.2.2 palmitoyl-CoA hydrolase
3.1.2.20 acyl-CoA hydrolase
3.1.2.21 dodecanoyl-[acyl-carrier-protein] hydrolase




8,11,14-eicosatrienoic_acid + ferricytochrome_b5 + O2 + H+ <=> arachidonic_acid + ferricytochrome_b5 + H2O 1.14.19.30 acyl-lipid (8-3)-desaturase
1.14.19.44 acyl-CoA (8-3)-desaturase


a_very-long-chain_(3R)-3-hydroxyacyl-CoA <=> very-long-chain_(2E)-2-enoyl-CoA + H2O 4.2.1.134 very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase

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